You're sending emails from your Python app with the Twilio SendGrid API and want to attach files, making it straightforward to include attachments using the Twilio SendGrid API. To start, you need a free Twilio SendGrid account and install the Twilio SendGrid Python Library in your project. You should also set up an environment variable for the SendGrid API key to avoid hardcoding it in your code. Running the code in a virtual environment is recommended to isolate the environment. The code uses the base64 module to encode the file as a string, then creates an attachment using the Twilio SendGrid helper libraries and sends the email with the attached file. Finally, you can save the code, set up the environment variable, replace the placeholder values, and run the command to send yourself an email to verify that it worked correctly. With this setup, you can add attachments to your emails sent with Twilio SendGrid and explore more features of the API.