Monitoring the performance of a Node.js application built on top of a graph database like Neo4j can be challenging due to its complex service infrastructure and asynchronous JavaScript elements. Ruxit Agent can help by automatically discovering service dependencies, monitoring load, response times, and visualizing the topology of applications in real-time. By installing Ruxit Agent on the host machine, developers can gain insights into how their application performs under load, identify bottlenecks, and optimize their Neo4j database for better performance. The tool provides a smartscape view that shows the service communication between the Node.js application and the underlying Neo4j browser UI requests, as well as user requests to the application's webpage. By analyzing this topology, developers can gain valuable insights into how their application is performing and make data-driven decisions to improve its performance.