The NODES 2021 conference featured a wide range of sessions and talks on graph databases, including the world's biggest graph database demo and presentations from industry experts like Emil Eifrem, CEO of Neo4j. The conference covered various topics such as building graph-powered applications, AI & ML with graph data science, graph-native scaling, and creating graphs with Arrows.app. Additionally, there were talks on using Neo4j and GraphQL, information extraction pipelines, machine learning pipelines in Neo4j, and visualizing graph data. Some notable sessions included a deep dive into building a link prediction model in Neo4j and using knowledge graphs to combat the medical climate crisis. The conference also featured interviews with community members and customers who shared their graph stories and experiences with Neo4j.