Many of the world's greatest scientific breakthroughs and inventions have been due to serendipity or accidental discoveries. In startups, creating an environment that encourages exploration and open-mindedness can lead to unexpected successes. The article suggests five key takeaways for fostering serendipity in a startup: 1) Recognize multiple routes to success; 2) Provide space for exploration; 3) Look for the "that's funny" moment when something doesn't go as planned; 4) Double-down on things that are going well; and 5) Pay strong attention to user feedback. By following these principles, startups can increase their chances of experiencing serendipitous discoveries and pivoting towards success.