Buildkite serves advanced development teams that often use monorepos, or monolithic repositories, which store all code for multiple projects in a single repository. This approach simplifies dependency management, code sharing, visibility, collaboration, release processes, and standardization across projects. However, monorepos can also present challenges such as scaling issues with CI/CD tools, keeping the main branch clean, managing merge conflicts, and maintaining clean code practices. To address these, strategies like selective builds, effective dependency management, access control, employing Git features like shallow clones and sparse checkouts, trunk-based development, and merge queues are recommended. Buildkite provides features such as dynamic pipelines, unlimited build agents, and customizable workflows that help manage the complexities of monorepos, aiding companies like Shopify, Uber, and Slack in optimizing their development workflows.