The "red flag" meme and other popular Twitter meme formats can be inaccessible to users with screen readers, which can lead to a poor user experience. To make your web content accessible on Twitter, consider the following tips: using single images without text in the tweet itself, adding descriptive alt text to every image you post, tweaking GIFs to include more accurate and inclusive alt text, avoiding red flag emoji spam, and being mindful of formatting when creating aligned text memes or using special Unicode characters. By implementing these adjustments, you can ensure that your tweets are accessible to users with screen readers and provide a better experience for everyone.