Zoho is a capable CRM that offers a simple but effective solution for managing customer relationships at a lower cost, while Salesforce is a premium option with more complex features, better suited for larger businesses or those who need advanced automation and scalability. Zoho excels in basic task management and issue tracking, while Salesforce has a broader range of integrations and customization options. Both platforms offer AI assistants, but Zoho's is cheaper and equally effective.