To create an effective customer support portal, companies can use Zapier's Interfaces and Tables features to build a self-service resource hub for their customers. The process involves creating a template, customizing it with layouts such as a ticket submission form, Kanban view, and link cards, and connecting them to a database via Zapier Tables. The portal can also be integrated with AI chatbots and automated workflows using Zaps, allowing customers to self-serve or submit tickets for support. With the setup of these features, companies can streamline their customer support process, improve response times, and enhance the overall customer experience.