slack offers two options to set up autoreplies: the Status feature, which lets everyone know what you're up to, and Slackbot, which can automatically respond to specific words or phrases with a pre-set message. The Slackbot option is useful for responding to common questions or setting up an out-of-office autoresponder. Both features allow users to quickly set up autoreplies without having to manually change their status when they're on vacation. Additionally, there's also the possibility of using Zapier to build more complex autoreplies and automate Slack status updates with Google Calendar.