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Copilot is a more integrated and tailored way of searching for answers, built into Microsoft's search engine and available in the Microsoft Edge browser. It offers features such as contextual summaries, image generation, and voice capabilities, making it a powerful research tool. Copilot also allows users to enable plugins to extend its functionality, but the options are limited compared to ChatGPT. On the other hand, ChatGPT is an isolated interface that uses OpenAI's GPT model and offers more integrations and plugins with apps like Zapier. ChatGPT makes it easy to share conversations, whereas Copilot has a clunkier sharing experience. Ultimately, the better option depends on the user's actual use case, with Copilot being suitable for research tools integrated with web browsers and ChatGPT being better suited for personal assistants that can perform actions in different apps.