The best note-taking apps for Windows are Microsoft OneNote, Obsidian, Simplenote, and Joplin. These apps cater to different needs and preferences, with Microsoft OneNote being the most feature-rich and user-friendly, while Obsidian offers high customization options and a large add-on ecosystem. Simplenote is ideal for those who want a simple and straightforward note-taking experience, and Joplin provides an open-source option with local storage and syncing capabilities. Each app has its strengths and weaknesses, making them suitable for different users and use cases.