B2B email marketing requires a tailored strategy that differs from consumer outreach, as it targets companies and multiple individuals within those companies. Minor tweaks to generalized email marketing tactics are not enough to create success, and instead, marketers need to focus on providing information and resources that cater to the needs and interests of the recipient. This involves identifying the buying center of the target company, segmenting emails based on individual roles, planning campaigns in stages, using templates, automating tasks, and leveraging AI to generate content and optimize subject lines. Effective B2B email marketing strategies involve personalizing emails, keeping them scannable, and using a mix of educational content, curated resources, and calls-to-action that resonate with the target audience. By following these best practices, marketers can achieve significant returns on investment, with some campaigns yielding as much as 4,200% ROI.