This tutorial guides users through setting up an Amazon Transcribe & Comprehend reference connection and a sample application using Vonage Voice API. The process involves setting up AWS AI platforms, including transcription engine Amazon Transcribe and sentiment analysis engine Amazon Comprehend, to enable real-time audio streaming of each party's voice via WebSockets from the Vonage platform. The application allows two parties to connect for a conference call, with separate real-time transcription and sentiment analysis for each party's speech. The setup requires a Vonage API account, virtual phone number, and server public hostname and port information, which are used to set up the sample application and test drive the integration architecture.