This tutorial guides developers on setting up a basic Amazon Lex bot, creating a Lex reference connection for two-way audio streaming, and integrating a Vonage Voice API application to handle incoming calls and interact with the Lex bot via voice. To complete this tutorial, developers need an Amazon Web Services account and a Vonage API account, as well as a virtual phone number. The tutorial covers setting up an example Amazon Lex bot, publishing it, creating a Lex reference connection, deploying a Lex sample Voice API application, and improving the Lex bot to play a greeting and confirmation message.