The Bref serverless framework allows developers to create and deploy serverless applications, called functions, on AWS Lambda using PHP. The framework integrates with the Serverless Framework, which abstracts operations involved in deploying and monitoring such applications. A webhook is created to forward Twilio application errors to a Slack channel, enabling real-time error tracking and notification. To set up the project, developers need PHP 7.2 or later, an AWS account, a Twilio account, Composer and npm installed, and a Slack Hook URL. The project requires installing the AWS CLI and serverless binary, creating a Bref project, handling incoming errors, setting up AWS credentials, and deploying to AWS Lambda.