Two-factor authentication is being emphasized as a crucial security measure for businesses in 2013, with Twilio highlighting its benefits and potential applications. The use of phone-based token delivery, or out-of-band communication, is seen as an effective way to protect against password hacks and other cyber threats. With billions of mobile phones and landlines available, this approach offers a cost-effective alternative to traditional security solutions such as expensive tokens and password generators. Twilio provides a platform for businesses to deliver one-time passwords via SMS or voice calls, allowing for greater flexibility in restricting the time to live of a password and improving user experience. Implementing two-factor authentication can be a simple and effective way to strengthen existing infrastructure and make business sense, according to Twilio.