Graph Centers of Excellence (CoEs) are gaining popularity as organizations increasingly adopt graph databases to stay ahead in the rapidly changing business landscape. These specialized teams help standardize workflows, tools, and methodologies while driving innovation through graph technology. Key operational strategies for a successful Graph CoE include building a portfolio of use cases, sharing success stories, tracking return on investment (ROI), fostering training and advocacy, and creating an idea pipeline. Challenges in starting a Graph CoE include finding professionals with knowledge of graph databases and leadership skills, overcoming resistance to change, and integrating graph technologies into existing systems. By focusing on these strategies and addressing challenges, organizations can effectively leverage the power of graph technology for enhanced decision-making and positive change.