Multi-tenancy in Strapi is a critical concept that can vary in meaning. It refers to a software architecture where a single application instance serves multiple tenants (clients or projects) isolated manner. True multi-tenancy requires careful isolation of data and configurations, whereas "multi-site" management often means managing multiple sites or clients with shared infrastructure. Strapi intentionally does not support true multi-tenancy in a single instance due to its limitations, security concerns, and potential performance bottlenecks. Instead, the recommended approach is to adopt a multi-instance architecture: one Strapi project per client, site, or application. This provides clear isolation, customizability, simplified maintenance, stronger security, and scalability. Strapi Cloud offers convenience and scalability for teams managing multiple clients or brands, while monorepos and shared codebases enable easier updates across instances. Advanced users may experiment with custom tenant-aware data models and middleware, but these setups require deep customization and ongoing maintenance.