Creating a secure Python package involves several steps, including setting up a directory structure, creating package files, configuring metadata, testing, and publishing to PyPI or a private index. To create a package, developers need to review installation and importation methods, use public-facing packages from PyPI or private indexes, configure the build system using tools like setuptools, and specify dependencies in the `pyproject.toml` file. The package should also include clear documentation, tests, and resource files, as well as a license and version number. To ensure security, developers should review dependencies, be careful with strings and raw SQL, deserialize cautiously, remove secrets securely, and use tools like Synk to scan for vulnerabilities. By following these steps and best practices, developers can create secure and reusable Python packages that are easy to install and maintain.