Jerry Liu, Co-Founder and CEO of LlamaIndex, shared his expertise on building advanced knowledge assistants using Large Language Models (LLMs) and agentic reasoning at the SingleStore NOW 2024 Conference. The key components for creating a more powerful and production-ready knowledge assistant include overcoming traditional Retrieval Augmented Generation (RAG) limitations, building a high-quality data layer through accurate document parsing and indexing, and incorporating agentic reasoning to tackle complex tasks. This approach enables AI systems to deliver high-value outputs and automate knowledge work, with potential applications in domains like financial analysis, customer support automation, and decision-making processes.