Python has emerged as a popular programming language, especially in data analytics and scientific programming. The current state of Python-based REST API frameworks includes various options such as Requests, Faster Than Requests, PycURL, Flask, Tornado, FastAPI, Sanic, Falcon, Bottle, Hug, Eve, Django, TurboGears, web2py, and Pyramid. Each framework has its strengths and weaknesses, with some being designed for performance, reliability, or ease of use. The choice of a framework depends on factors such as the role played by the framework, scope, scale, and time constraints. Some frameworks are suitable for building full-fledged web applications, while others are better suited for microservices, client-side HTTP requests, or lightweight web application backends.