The COVID-19 pandemic led to a significant increase in cyberattacks as businesses shifted to digital platforms, resulting in a 300% rise in cybercrime reports and a 650% increase in software supply chain attacks. Cybersecurity professionals face challenges in defending against attackers who think in graphs, while defenders traditionally rely on lists, creating blind spots. Graph databases can help defenders build a complete graph of their infrastructure, enriching it over time, and provide a high-fidelity model of the real world, integrating many data sources and revealing dependencies. By modeling infrastructure as a graph, defenders can identify valuable assets, generate alerts for relevant teams, analyze suspicious behavior, and conduct ongoing cyber risk assessment, ultimately gaining predictive, preemptive, and proactive threat identification and management capabilities.