Company
Date Published
Author
Shobhna Srivastava & Helena Deus PhD
Word count
784
Language
English
Hacker News points
None

Summary

Elsevier, a Dutch publishing company, is utilizing Neo4j graph technology to analyze its vast network of scientific content related to COVID-19. The project, Core Citation Graph (C-Graph), aims to query the network and provide insights into drug repurposing for COVID-19 treatment. By applying graph technology, Elsevier was able to build a polypharmacology model, predict effective drug combinations, and identify key proteins related to coronaviruses such as SARS-CoV-1 and MERS-CoV. The Neo4j platform enabled the team to collect and analyze data efficiently, producing simplified graphs that helped researchers understand COVID-19 mechanistic pathways in a matter of weeks. This technology is expected to be used beyond COVID-19 research, supporting studies into immunological diseases and enabling more targeted insights for researchers.