The creator of py2neo, Nigel Small, has announced that the project is end-of-life. The Neo4j community is grateful for his work and legacy. Py2neo elegantly bridged graph thinking with Pythonic principles, but its maintenance has ceased. For ongoing work with Neo4j in Python, it is recommended to migrate to the official driver or neomodel. Neomodel is an open-source Python OGM (Object Graph Model) for Neo4j that ensures a good level of code quality and maintenance. The guide outlines the steps to migrate from py2neo to neomodel, including installing neomodel, updating imports, connecting to Neo4j, performing Cypher querying, defining objects and relationships, indexing, testing, and creating objects. Some features of py2neo are not covered by neomodel yet, such as converting results to pandas DataFrame/Series and numpy ndarray objects. The guide concludes with a call for feedback and support from the Neo4j community forum or GitHub issues.