The Neo4j Query API offers a more streamlined experience with versioning, implicit and explicit transactions, and a single Cypher statement per request. The URL paths have changed to include the API name and support versioning, allowing for gradual migration without interruption. The Query API also includes response notifications with categorization, JSON with type information, and changes in the response format. When planning your migration, it's essential to be curious about your application's usage, remember that a slow and steady approach is better than a hasty swap-over, take advantage of running both APIs for back-to-back testing, and read the Query API documentation thoroughly.