Screen reader accessibility testing is crucial for ensuring smooth digital experiences for individuals who depend on assistive technologies like screen readers to consume digital content. This involves evaluating the ease of navigation and comprehension of a website or mobile application using a screen reader. Popular screen readers include JAWS, NVDA, TalkBack, and VoiceOver. The process includes setting up screen readers, learning their navigation techniques, preparing a test plan, running tests, and following best practices for testing. Automated tools like LambdaTest can also be used to perform accessibility testing using screen readers across multiple environments.