Azure Blob Storage is used with InfluxDB 3 Core and Enterprise to store time series data in cloud object storage while running the database engine locally. This approach offers significant advantages, including performance combined with durability, scalability, and cost-effectiveness of cloud storage. To set up Azure Blob Storage, an Azure account with access to create storage resources is needed, along with a terminal or command prompt with necessary permissions. The process involves creating an Azure Storage account and container, obtaining access credentials, and configuring InfluxDB to use Azure as an object store. With this configuration, data is persistently stored in Azure Blob Storage while the database engine runs on the local machine. This setup provides high availability, workload distribution, and cost-effectiveness for organizations with existing Azure infrastructure, applications requiring high durability without complex local storage management, multi-region deployments, and cost-effective long-term storage for time series data.