To get started with JavaScript and InfluxDB 2.0, users can use the InfluxDB v2 JavaScript Client Library to perform data collection, write points, query data, and monitor database health. The library requires authorization parameters such as org, bucket, and token, which can be obtained from the InfluxDB UI or created through the InfluxDB console. The client library supports various data formatting methods, including writing line protocol data to InfluxDB and querying data using Flux queries. Additionally, the library includes examples for onboarding users, performing health checks, and visualizing time series data with Giraffe and Clockface.