This article provides a step-by-step guide on setting up a DataStax Enterprise cluster running in a single host. The goal is to create a dense node with multiple DataStax Enterprise database only nodes in a single cluster. The process involves downloading and unpacking DataStax Enterprise, creating directories for each node's configuration files, data, and logs, copying configuration files, editing configuration files, setting environment variables, and starting the nodes. Additionally, scripts are provided to automate the setup process. The article also covers configuring a cluster of DSE Search nodes using the same steps with some DSE Search specific tweaks.