The article discusses the combination of TypeORM and CockroachDB as a powerful database solution for TypeScript applications. It explains that TypeORM is an ORM library that supports various databases, including CockroachDB, which is a cloud-native distributed SQL database with features like online schema changes, automated data replication, and elastic scaling. The article provides a step-by-step guide on how to connect a TypeScript application to CockroachDB, emphasizing its ease of use and performance benefits.