This guide provides detailed steps for replacing Twilio's delegate design pattern with Agora's singleton design pattern in an iOS application. The process involves creating an easily accessible variable, replacing the Twilio video pod and import statements, removing four delegates, initializing an instance of the Agora singleton, enabling video, configuring the canvas or video, joining a channel, and handling disconnection and other features. By following these steps, developers can adopt Agora's voice, video, and live-broadcasting software for their applications, leveraging its Software Defined Real-Time Network (SD-RTN™) infrastructure.